Purdue University
Reifenberger Nanophysics Lab
find out more

Recent Publications

  > Browse recent publications

Search Engines and Directory:

-Search Physics:

-Search Purdue:

-Univ. Directory:
Restrict Search by Campus

Cantilever Sensing

Microcantilevers designed for atomic force microscopy have been successfully used as extremely sensitive chemical, physical and biological sensors. A biosensor employs a biological or biochemical detector, which can range from single proteins and enzymes up to whole cells and microorganisms. In recent years, Biomolecules and their unique ability of molecular recognition have been investigated in terms of their mechanical response to external forces. One of the latest efforts in this field has been to measure mechanical responses of thin beams of silicon (microcantilevers) arranged in a microfabricated array. This is achieved by coating one side of these cantilevers with a sensor layer that shows an individual response to analyte molecules. The intermolecular forces arising from adsorption of these small analyte molecules are known to induce surface stress, directly resulting in the mechanical bending of cantilevers. Also, mass uptake of a targeted analyte is reflected as a change in resonant frequency. We can take advantage of biochemically induced cahnges to directly and specifically transduce molecular recognition into nano mechanical responses in a cantilever array.

Our work on cantilever array sensing is of direct interest to Purdue's Center for Sensing Science and Technology (CSST).



Click Here to go Back