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Rosalyn Yalow's primary accomplishment involves
the creation of a new analytic technique called the radioimmunoassay,
or the RIA. This technique allowed quantifying very small amounts of
biological substances in body fluids using radioactive-labeled
material. This made it possible to diagnose conditions caused by
minute changes in hormone levels. RIA was used in 1951 to show that
adult diabetics did not always suffer from insuffiency of insulin in
their blood and that some unknown factor must be blocking the action
of insulin.
Many practical uses were discovered for RIA. It
has been used to screen blood for hepatitis virus in blood banks, to
determiune effective dosage levels of drugs and antibiotics, to detect
foreign substances in the blood, and to test and correct hormone
levels in infertile couples.
Yalow has received many awards throughout her
career. In 1976, she became the first woman to be awarded the Albert
Lasker Prize for Basic Medical Research. She shared the Nobel Proze in
Physiology or Medicine in 1977 for her RIA work. And in 1988, she was
awarded the National Medal of Science, the nation's highest science
award.
Source:
Biography of
Rosalyn Sussman Yalow, Danuta Bois.
Distinguished
Women of Past and Present.
Photograph of Rosalyn Sussman
Yalow © CWP and Regents of the University of California.
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