Publications and Talks

Refereed

• Wei, Q., Song, H.-M., Leonov, A. P., Hale, J. A., Oh, D., Ong, Q. K., Ritchie, K. and Wei, A. (2009)
  Gyromagnetic Imaging: Dynamic Optical Contrast Using Gold Nanostars with Magnetic Cores.
  J Am Chem Soc., 131:9728-9734
  
  
• Kodippili, G. C., Spector, J., Sullivan, C., Kuypers, F. A., Labotka, R., Gallagher, P. G., Ritchie, K. and Low, P. S. (2009)
  Imaging of the diffusion of single band 3 molecules on normal and mutant erythrocytes.
  Blood, 113: 6237-6245.
  
  
• Yu, C., Hale, J., Ritchie, K., Prasad, N. K and Irudayaraj J. (2009)
  Receptor overexpression or inhibition alters cell surface dynamics of EGF-EGFR interaction: new insights from real-time single molecule analysis.
  Biochem. Biophys. Res. Comm. 378:376-82.
  
  
• Murcia, M. J., Minner, D. E., Mustata, G. M., Ritchie, K. and Naumann, C. A. (2008)
  Design of Quantum Dot-Conjugated Lipids for Long-Term, High-Speed Tracking Experiments on Cell Surfaces.
  J Am Chem Soc., 130:15054-15062.
  
  
• Simon, S. I., Nyunt, T., Florine-Casteel, K., Ritchie, K., Ting-Beall, H. P., Evans, E. and Needham, D. (2007)
  Dynamics of neutrophil membrane compliance and microstructure probed with a micropipet-based piconewton force transducer.
  Ann. Biomed. Eng. 35:595-604.
  
  
• Suzuki, K., Ritchie, K., Kajikawa, E., Fujiwara, T. and Kusumi, A. (2005)
  Rapid hop diffusion of a G-protein-coupled receptor in the plasma membrane as revealed by single-molecule techniques.
  Biophys. J. 88:3659-3680.
  
  
• Ritchie, K., Shan, X.-Y., Kondo, J., Iwasawa, K., Fujiwara, T. and Kusumi A. (2005)
  Detection of non-Brownian diffusion in the cell membrane in single molecule tracking.
  Biophys. J. 88:2266-2277.
  
  
• Koyama-Honda, I., Ritchie, K., Fujiwara, T., Iino, R., Murakoshi, H., Kasai, R.S. and Kusumi, A. (2005)
  Fluorescence imaging for monitoring the colocalization of two single molecules in living cells.
  Biophys. J. 88:2126-2136.
  
  
• Murase, K., Fujiwara, T., Umemura, Y., Suzuki, K., Iino, R., Yamashita, H., Saito, M., Murakoshi, H., Ritchie, K. and Kusumi A. (2004)
  Ultrafine membrane compartments for molecular diffusion as revealed by single molecule techniques.
  Biophys. J. 86:4075-4093.
  
  
• Nakada, C., Ritchie, K., Oba, Y., Nakamura, M., Hotta, Y., Iino, R., Kasai, R. S., Yamaguchi, K., Fujiwara, T. and Kusumi, A. (2003)
  Accumulation of anchored proteins forms membrane diffusion barriers as neurons develop polarization.
  Nat. Cell Biol., 5:626-632.
  
  
• Ike, H., Kosugi, A., Kato, A., Iino, R., Hirano, H., Fujiwara, T., Ritchie, K. and Kusumi, A. (2003)
  Mechanism of Lck recruitment to the T-cell receptor cluster as studied by single molecule fluorescence video imaging.
  ChemPhysChem 4:620-626.
  
  
• Ritchie K. and Kusumi A. (2002)
  Single molecule probe scanning optical force imaging microscope for viewing live cells.
  J. Biol. Phys. 28:619-626.
  
  
• Fujiwara, T., Ritchie, K., Murakoshi, H., Jacobson, K. and Kusumi, A. (2002)
  Phospholipids undergo hop diffusion in compartmentalized cell membrane.
  J. Cell Biol. 157:1071-1081.
  
  
• Heinrich, V., Ritchie, K., Mohandas, N., and Evans E. (2001)
  Elastic Thickness Compressibility of the Red Cell Membrane.
  Biophys. J., 81:1452-1463.
  
  
• Evans, E. and Ritchie, K. (1999)
  Rupture of a Weak Bond Connecting Flexible Polymer Chains.
  Biophys. J., 76:2439-2447.
  
  
• Merkel, R., Nassoy, P., Leung, A., Ritchie, K., and Evans, E. (1998)
  Using Dynamic Force Spectroscopy to Explore Energy Landscapes of Receptor-Ligand Bonds.
  Nature, 397:50-53.
  
  
• Evans, E. and Ritchie, K. (1997)
  Dynamic strength of molecular adhesion bonds.
  Biophys. J., 72:1541-1555.
  
  
• Leung, S.-M., Senisterra, G., Ritchie, K.P., Sadis, S.E., Lepock, J.R. and Hightower, L.E. (1996)
  Thermal activation of bovine hsc70 molecular chaperone at physiological temperatures: Physical evidence of a molecular thermometer.
  Cell Stress and Chaperones, 1:78-89.
  
  
• Evans, E., Ritchie, K., and Merkel, R. (1995)
  Ultrasensitive Force Technique to Probe Molecular Adhesion and Structure at Biological Interfaces.
  Biophys. J., 68:2580-2587.
  
  
• Ritchie, K.P., Keller, B.M., Syed, K.M., and Lepock, J.R. (1995)
  Hyperthermia (Heat Shock)-Induced Protein Denaturation in Liver, Muscle, and Lens Tissue as Determined by Differential Scanning Calorimetry.
  Int. J. Hyperthermia, 10:605-618.
  
  
• Lepock, J.R., Frey, H.E., and Ritchie, K.P. (1993)
  Protein Denaturation in Intact Hepatocytes and Isolated Cellular Organelles during Heat Shock.
  J. Cell. Biol., 122, no. 6:1267-1276.
  
  
• Lepock, J.R., Ritchie, K.P., Kolios, M.C., Rodahl, A.M., Heinz, K.A., and Kruuv, J. (1992)
  Influence of Transition Rates and Scan Rate on Kinetic Simulations of Differential Scanning Calorimetry Profiles of Reversible and Irreversible Protein Denaturation.
  Biochem., 31:12706-12712.
  
  
• Lepock, J.R., Frey, H.E., Heynen, M.P., Nishio, J., Waters, B., Ritchie, K.P., and Kruuv, J. (1990)
  Increased Thermostability of Thermotolerant CHL V79 as Determined by Differential Scanning Calorimetry.
  J. Cell. Physiol., 142:628-634.
  
  

Books, Chapters and Invited Reviews

• Ritchie, K. and Spector, J. (2007)
  Single molecule studies of molecular diffusion in cellular membranes: Determining membrane structure.
  Biopolymers (Invited Review) 87, 95-101.
  
  
• Kusumi, A., Nakada, C., Ritchie, K., Murase, K., Suzuki, K., Murakoshi, H., Kasai, R.S., Kondo, J. and Fujiwara T. (2005)
  Paradigm Shift Of The Plasma Membrane Concept From The Two-Dimensional Continuum Fluid To The Partitioned Fluid: High-Speed Single-Molecule Tracking of Membrane Molecules.
  Annu. Rev. Biophys. Biomol. Struct. 34: 351-378.
  
  
• Ritchie, K. and Kusumi A. (2004)
  Role of the membrane skeleton in creation of microdomains.
  Subcellular Biochem. 37:233-245.
  
  
• Ritchie, K. and Kusumi, A. (2003)
  Single particle tracking image microscopy.
  Methods In Enzymol, 360 "Biophotonics", G. Marriott and Ian Parker, editors. pp. 618-634.
  
  
• Fujiwara, T., Ritchie, K., Yamashita, H., and Kusumi, A. (2003)
  (Use of optical tweezers for single molecule manipulation)
  in (Nanophotonics Engineering Handbook). Asakura Publishing.
  
  
• Ritchie, K., Iino, R., Fujiwara, T., Murase, K. and Kusumi, A. (2002)
  The fence and picket structure of the plasma membrane of live cells as revealed by single molecule techniques (Review).
  Mol. Memb. Biol 20:13-18.
  
  
• Murase, K., Ritchie, K., Fujiwara, T., Iino, R., Nakada, C., and Kusumi, A. (2002)
  (Regulation mechanisms for molecular diffusion in the cell membrane by the membrane skeleton: A single molecule approach).
  Membrane, 27: 58-66.
  
  
• Ritchie, K. (2002)
  (Optical tweezers and scanning optical force microscopy)
  in (Understanding modern bioimaging), Kusumi, A., Kobayashi, T., Yoshimura Editors, (Experimental Medicine, Special Volume) 20, No. 5, 121-125.
  
  
• Fujiwara, T., Ritchie, K. and Suzuki, K. (2001)
  (Single molecule observation and manipulation EInvestigations of compartments and domains in cell membranes),
  (Cell Technology) 20, 697-703.
  
  
• Evans, E., Merkel, R., Ritchie, K., Tha, S., and Zilker, A. (1994)
  Picoforce Method to Probe Submicroscopic Actions in Biomembrane Adhesion.
  In Methods for Studying Cell Adhesion. Bongrand, Claesson and Curtis Eds., Springer-Verlag, Berlin.
  
  
• Evans, E., and Ritchie, K. (1994)
  Probing Molecular Attachments to Cell Surface Receptors: Image of Stochastic Bonding and Rupture Processes.
  In Scanning Probe Microscopies and Molecular Materials. Rabe, J., Gaub, H. and Hansma, P. eds. Kluwer Publ., Amsterdam.