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Purdue University - Weldon School of Biomedical Engineering

"Bond-selective Imaging: A New Window into the Unseen World"

Thursday February 28, 2013

4:00pm phys203

Refreshments are served at 3:30 p.m. in Physics room 242

Label-free spectroscopic imaging using inherent chemical bond vibration signals as contrast opens a new window for watching biomolecules and nanomaterials inside living cells and even the human body. Major advances have been made to allow real time imaging of living systems, to extract significant information from the crowded fingerprint bands of a biological system, and to obtain spectroscopic information from a tissue that is centimeter deep under the surface. I will present our most recent advances in both development and applications of spectroscopic imaging platforms, including deep tissue imaging by listening to harmonic molecular vibration, study of lipid metabolism in cancer by coherent Raman microscopy, and super-resolution imaging of nanomaterials by transient absorption microscopy. Potentially transformative impacts of these projects will be illustrated.