March 29 - 4:00pm Phys 223
(Coffee at 3:30p.m. in room 242)
Prof. R. Graham Cooks
Chemistry Department
Purdue University
Title: "Ion Trap Mass Spectrometry"
Mass spectrometry has rapidly become one of the most important analytical tools in science. This talk surveys the applications and details the fundamentals of mass spectrometry as carried out using the quadrupole ion trap invented by Wolfgang Paul. A general introduction to mass analyzers and ionization methods is followed by a survey of ion trap capabilities and applications. The fundamentals of ion motion in the ion trap are explored using computer simulations and experiments. Numerical simulations allow the motion of a population of ions in an oscillating electric field to be followed. The simulations are used to guide new experiments including measurements of ion resonance frequencies and elastic scattering cross-sections. On-line, in situ monitoring of chemical and biological reactors is described. Miniature ion traps and arrays of traps are shown to be useful in a variety of practically important applications.
Bio:
Education
B.S. University of Natal, South Africa 1961
Ph.D. University of Natal, South Africa 1965
Ph.D. Cambridge University, Great Britain 1967
Professional Experience and Visiting Positions
Post-doctoral Fellow, Cambridge University 1967-1968
Assistant Professor, Chemistry Dept., Kansas State Univ. 1968-1971
Co-Director and Director, Mass Spectrometry Center, Purdue Univ. 1971-1986
Associate Professor of Chemistry, Purdue University 1975-1979
Professor of Chemistry, Purdue University 1980-present
Fulbright Senior Fellow, University of Warwick 1981
Adjunct Professor, Beijing Institute of Technology 1987-present
Head, Analytical Division, Purdue University 1989-1996
Henry Bohn Hass Distinguished Professor of Chemistry, Purdue University 1990-present
Honors
Elsie Ballot Scholar, Cambridge University, 1965-1967; Fulbright Senior Fellow, University of Warwick 1981; American Chemical Society, Analytical Division, Award in Chemical Instrumentation 1984;
Thomson Medal for Mass Spectrometry 1985; Purdue Sigma Xi Faculty Research Award 1986; President, American Society for Mass Spectrometry, 1986-1988; Honorary Member of Chinese Mass Spectrometry Society 1987; Herbert Newby McCoy Award 1990;Frank H. Field & Joe L. Franklin Award, (ACS Award for Mass Spectrometry) 1991; Fisher Award (ACS Award for Analytical Chemistry) 1997; President, International Mass Spectrometry Society, 1997-present; D. Sc. (honoris causa) University of Natal, 1999.
Current Graduate Students: 19 students (73 Ph. D. students advised).
Research Achievements
Several new types of mass spectrometers have been constructed in Prof. Cooks’ laboratory, including hybrid sector/quadrupole instruments, ion trap instruments capable of MS/MS experiments and cylindrical ion trap and arrays. His group made significant contributions to the development of desorption ionization and tandem mass spectrometry as methods of analysis of complex mixtures. His work on the kinetic method of measuring thermochemical quantities is one outcome of his interest in ion structure and fragmentation mechanism. He has done pioneering work in the area of inelastic and reactive ion collisions with surfaces. He has received research awards for chemical instrumentation, tandem mass spectrometry and analytical chemistry and has been recognized for his service to mass spectrometry, both nationally and internationally.
Editorial boards
Accounts of Chemical Research (1993-1995); Mass Spectrometry Reviews (1988-1990; 1999-present); International Journal of Mass Spectrometry and Ion Processes (1987-present); Rapid Communications in Mass Spectrometry (1986-present); Journal of Mass Spectrometry (1984-present); Talanta (1984-present); Journal of the American Society for Mass Spectrometry (1989-1996; 1997-present); Anal. Chim. Acta (1993-present).
Publications
645 publications to date